Endocrine Abstracts

The population of the world is aging and is estimated that by 2030 – 21% of global population will be aged 65 years and older. At present, under-nutrition in older people is a serious and growing global problem affecting even developed countries. As one ages, several physiological and pathlogical changes may contribute towards the development of protein energy malnutrition. This syndrom brings with it many adverse health outcomes and a significant cost to the individual, ...

Background: Excess mortality after hip fracture remains a problem of public health concern. Until present, for Romania no data is available regarding long term mortality rate and excess mortality after hip fracture. We aimed to evaluate the mortality rate 3 years after hip fracture and also standardized mortality rates of osteoporotic hip fracture in the capital city of Romania and suburban area.Methods: we collected data from over 98 % of fractures admi...

Background: Prolonged ingestion of licorice has been known to cause hypokalemia and resistant hypertension amongst other disturbances. This is due to glycyrrhizin that inhibits the 11-β-hydroxysteroid dehydrogenase enzyme type 2 which results into increased plasma cortisol levels that stimulate the mineralocorticoid receptors resulting into apparent mineralocorticoid excess.Case report: A 45-year-old woman resident in an iodine sufficient area, heav...

Background: Active acromegaly is characterized by decreased insulin sensitivity (ISen). However, insulin secretion (ISec) may not increase satisfactorily to compensate for the low ISen.Aim: To assess ISen and ISec and to calculate disposition index (DI) using an intravenous glucose tolerance test (IVGTT) in patients with active acromegaly.Methods: Twelve patients (7 men, 5 women) with active acromegaly and 2 normal subjects (2 men)...

Background: Melatonin is mostly known as a circadian hormone, but it also has effects in a large number of cellular processes (cell differentiation, proliferation, apoptosis, redox balance). Although it was studied in many tumours, very little is known about his role in pharyngo-laryngeal carcinomas.Aim: To evaluate serum melatonin levels in patients with pharyngo-laryngeal malignant tumours preoperatively and after surgical excision of the malignancy.</...

Introduction: The heel quantitative ultrasound (QUS) is useful tool in the assessment of fracture risk especially if cost issues are involved. It might be helpful in follow-up the patients who will not be treated with anti-osteoporotic drugs.Aim: To present the bone evaluation (DXA) after a period of time in patients who are initially assesed by both DXA and QUS.Material and patients: This is a prospective pilot study in a group of...

Hypogonadal osteoporosis may occur early, asymptomatic and diagnosis is long etiology is often laborious. Early diagnosis of gonadal failure prevention measures require changes already in the prepubertal bone, puberty or postpuberal to ensure adequate peak bone mass sex and age.Casuistry is represented by 57 patients, of which the: late puberty (26 cases) and premature ovarian failure (31 cases). To elucidate the etiologic diagnosis was clinical and labo...

It is known that the genetic similarity, embryonic and functional hypothalamic-pituitary-gonadal system has close correlation with hypothalamic-pituitary-thyroid axis. Recent research has suggested the existence of interactions between the gonad and the functional capacity of the thyroid.The study was performed on 93 cases admitted to the Endocrinology Clinic during 2005–2011, whose age ranged from 16–44 years. Correlate with clinical features ...

In the thyroid gland pathology, thyroadenitis prominently in their scope, whose etiologic diagnosis is often difficult to objectified and therapeutic attitudes are not yet codified today. mechanisms production in the thyroid thyroid lesions are still far from being elucidated, and concepts are still ongoing reshuffle. There is another explanation that can withstand a critical analysis of how the thyroid’s self tolerance is repealed and the breaking of tolerance in a row f...

Hypertension is the most common cardiovascular disease in the mass population and one of the most important public health problems. Is recognized as a major risk factor for atherosclerosis, particularly coronary localized, brain, kidney and leading cause of cardiovascular morbidity and mortality in most industrialized countries and overall.Our study was performed in 121 patients with endocrine disorders (hypercortisolism, acromegaly, hyperthyroidism, hyp...